SrasV1, Main, Exploration, bibRecord, 002689

Translation initiation of viral mRNAs

Identifieur interne : 002689 ( Main/Exploration ); précédent : 002688; suivant : 002690

Translation initiation of viral mRNAs

Auteurs : Marcelo L Pez-Lastra [Chili] ; Pablo Ramdohr [Chili] ; Alejandro Letelier [Chili] ; Maricarmen Vallejos [Chili] ; Jorge Vera-Otarola [Chili] ; Fernando Valiente-Echeverría [Chili]

Source :

Reviews in Medical Virology [ 1052-9276 ] ; 2010-05.

RBID : ISTEX:FA82ACC43D89E3B29F42BFE0780C0178E80FD4E4

English descriptors

Teeft :
- Bicistronic, Biochem, Biochim biophys acta, Biol, Biol chem, Biophys, Cell biol, Cell cycle, Cellular, Cellular mrnas, Cellular proteins, Chem, Codon, Copyright, Eif1, Eif3, Eif4a, Eif4e, Eif4f, Eif4g, Eifs, Embo, Emcv, Encephalomyocarditis virus, Entry site, Eukaryotic, Eukaryotic ribosomes, Eukaryotic translation initiation factor, Helicase, Hellen, Hepatitis, Host cell protein synthesis, Human rhinovirus, Initiation, Initiation codon, Initiation factors, Initiator trna, Internal initiation, Internal ribosome entry site, Internal ribosome entry sites, Ire, Ires activity, Ires elements, Ires factors, Ireses, Itafs, John wiley sons, Leaky scanning, Mrna, Nsp3, Nucleic acids, Pabp, Pestova, Picornavirus, Poliovirus, Protein, Protein synthesis, Reinitiation, Replication, Respiratory syndrome coronavirus, Ribosomal, Ribosomal subunit, Ribosomal subunits, Ribosome, Ribosome entry site, Ribosome shunting, Rna, Sarnow, Shunting, Sonenberg, Subunit, Translation, Translation initiation, Translational, Translational control, Untranslated, Untranslated region, Utrs, Viral, Viral ires, Viral mrna, Viral mrna translation, Viral mrnas, Viral proteins, Virol, Virus.

Abstract

Viruses depend on cells for their replication but have evolved mechanisms to achieve this in an efficient and, in some instances, a cell‐type‐specific manner. The expression of viral proteins is frequently subject to translational control. The dominant target of such control is the initiation step of protein synthesis. Indeed, during the early stages of infection, viral mRNAs must compete with their host counterparts for the protein synthetic machinery, especially for the limited pool of eukaryotic translation initiation factors (eIFs) that mediate the recruitment of ribosomes to both viral and cellular mRNAs. To circumvent this competition viruses use diverse strategies so that ribosomes can be recruited selectively to viral mRNAs. In this review we focus on the initiation of protein synthesis and outline some of the strategies used by viruses to ensure efficient translation initiation of their mRNAs. Copyright © 2010 John Wiley & Sons, Ltd.

Url:

https://api.istex.fr/ark:/67375/WNG-N1CLFBWG-C/fulltext.pdf

DOI: 10.1002/rmv.649

Affiliations:

Chili

Links toward previous steps (curation, corpus...)

to stream Istex, to step Corpus: 000F98
to stream Istex, to step Curation: 000F98
to stream Istex, to step Checkpoint: 000942
to stream Main, to step Merge: 002728
to stream Main, to step Curation: 002689

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Translation initiation of viral mRNAs</title>
<author><name sortKey="L Pez Astra, Marcelo" sort="L Pez Astra, Marcelo" uniqKey="L Pez Astra M" first="Marcelo" last="L Pez-Lastra">Marcelo L Pez-Lastra</name>
</author>
<author><name sortKey="Ramdohr, Pablo" sort="Ramdohr, Pablo" uniqKey="Ramdohr P" first="Pablo" last="Ramdohr">Pablo Ramdohr</name>
</author>
<author><name sortKey="Letelier, Alejandro" sort="Letelier, Alejandro" uniqKey="Letelier A" first="Alejandro" last="Letelier">Alejandro Letelier</name>
</author>
<author><name sortKey="Vallejos, Maricarmen" sort="Vallejos, Maricarmen" uniqKey="Vallejos M" first="Maricarmen" last="Vallejos">Maricarmen Vallejos</name>
</author>
<author><name sortKey="Vera Tarola, Jorge" sort="Vera Tarola, Jorge" uniqKey="Vera Tarola J" first="Jorge" last="Vera-Otarola">Jorge Vera-Otarola</name>
</author>
<author><name sortKey="Valiente Cheverria, Fernando" sort="Valiente Cheverria, Fernando" uniqKey="Valiente Cheverria F" first="Fernando" last="Valiente-Echeverría">Fernando Valiente-Echeverría</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:FA82ACC43D89E3B29F42BFE0780C0178E80FD4E4</idno>
<date when="2010" year="2010">2010</date>
<idno type="doi">10.1002/rmv.649</idno>
<idno type="url">https://api.istex.fr/ark:/67375/WNG-N1CLFBWG-C/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000F98</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000F98</idno>
<idno type="wicri:Area/Istex/Curation">000F98</idno>
<idno type="wicri:Area/Istex/Checkpoint">000942</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000942</idno>
<idno type="wicri:doubleKey">1052-9276:2010:L Pez Astra M:translation:initiation:of</idno>
<idno type="wicri:Area/Main/Merge">002728</idno>
<idno type="wicri:Area/Main/Curation">002689</idno>
<idno type="wicri:Area/Main/Exploration">002689</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main">Translation initiation of viral mRNAs</title>
<author><name sortKey="L Pez Astra, Marcelo" sort="L Pez Astra, Marcelo" uniqKey="L Pez Astra M" first="Marcelo" last="L Pez-Lastra">Marcelo L Pez-Lastra</name>
<affiliation wicri:level="1"><country xml:lang="fr">Chili</country>
<wicri:regionArea>Laboratorio de Virología Molecular, Instituto Milenio de Inmunología e Inmunoterapia, Centro de Investigaciones Médicas, Facultad de Medicina, Pontificia Universidad Católica de Chile, Marcoleta 391, Santiago</wicri:regionArea>
<wicri:noRegion>Santiago</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country wicri:rule="url">Chili</country>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">Chili</country>
<wicri:regionArea>Correspondence address: Laboratorio de Virología Molecular, Centro de Investigaciones Médicas, Facultad de Medicina, Pontificia Universidad Católica de Chile, Marcoleta 391, Santiago</wicri:regionArea>
<wicri:noRegion>Santiago</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ramdohr, Pablo" sort="Ramdohr, Pablo" uniqKey="Ramdohr P" first="Pablo" last="Ramdohr">Pablo Ramdohr</name>
<affiliation wicri:level="1"><country xml:lang="fr">Chili</country>
<wicri:regionArea>Laboratorio de Virología Molecular, Instituto Milenio de Inmunología e Inmunoterapia, Centro de Investigaciones Médicas, Facultad de Medicina, Pontificia Universidad Católica de Chile, Marcoleta 391, Santiago</wicri:regionArea>
<wicri:noRegion>Santiago</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Letelier, Alejandro" sort="Letelier, Alejandro" uniqKey="Letelier A" first="Alejandro" last="Letelier">Alejandro Letelier</name>
<affiliation wicri:level="1"><country xml:lang="fr">Chili</country>
<wicri:regionArea>Laboratorio de Virología Molecular, Instituto Milenio de Inmunología e Inmunoterapia, Centro de Investigaciones Médicas, Facultad de Medicina, Pontificia Universidad Católica de Chile, Marcoleta 391, Santiago</wicri:regionArea>
<wicri:noRegion>Santiago</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vallejos, Maricarmen" sort="Vallejos, Maricarmen" uniqKey="Vallejos M" first="Maricarmen" last="Vallejos">Maricarmen Vallejos</name>
<affiliation wicri:level="1"><country xml:lang="fr">Chili</country>
<wicri:regionArea>Laboratorio de Virología Molecular, Instituto Milenio de Inmunología e Inmunoterapia, Centro de Investigaciones Médicas, Facultad de Medicina, Pontificia Universidad Católica de Chile, Marcoleta 391, Santiago</wicri:regionArea>
<wicri:noRegion>Santiago</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vera Tarola, Jorge" sort="Vera Tarola, Jorge" uniqKey="Vera Tarola J" first="Jorge" last="Vera-Otarola">Jorge Vera-Otarola</name>
<affiliation wicri:level="1"><country xml:lang="fr">Chili</country>
<wicri:regionArea>Laboratorio de Virología Molecular, Instituto Milenio de Inmunología e Inmunoterapia, Centro de Investigaciones Médicas, Facultad de Medicina, Pontificia Universidad Católica de Chile, Marcoleta 391, Santiago</wicri:regionArea>
<wicri:noRegion>Santiago</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Valiente Cheverria, Fernando" sort="Valiente Cheverria, Fernando" uniqKey="Valiente Cheverria F" first="Fernando" last="Valiente-Echeverría">Fernando Valiente-Echeverría</name>
<affiliation wicri:level="1"><country xml:lang="fr">Chili</country>
<wicri:regionArea>Laboratorio de Virología Molecular, Instituto Milenio de Inmunología e Inmunoterapia, Centro de Investigaciones Médicas, Facultad de Medicina, Pontificia Universidad Católica de Chile, Marcoleta 391, Santiago</wicri:regionArea>
<wicri:noRegion>Santiago</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">Reviews in Medical Virology</title>
<title level="j" type="alt">REVIEWS IN MEDICAL VIROLOGY</title>
<idno type="ISSN">1052-9276</idno>
<idno type="eISSN">1099-1654</idno>
<imprint><biblScope unit="vol">20</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="177">177</biblScope>
<biblScope unit="page" to="195">195</biblScope>
<biblScope unit="page-count">19</biblScope>
<publisher>John Wiley & Sons, Ltd.</publisher>
<pubPlace>Chichester, UK</pubPlace>
<date type="published" when="2010-05">2010-05</date>
</imprint>
<idno type="ISSN">1052-9276</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1052-9276</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Bicistronic</term>
<term>Biochem</term>
<term>Biochim biophys acta</term>
<term>Biol</term>
<term>Biol chem</term>
<term>Biophys</term>
<term>Cell biol</term>
<term>Cell cycle</term>
<term>Cellular</term>
<term>Cellular mrnas</term>
<term>Cellular proteins</term>
<term>Chem</term>
<term>Codon</term>
<term>Copyright</term>
<term>Eif1</term>
<term>Eif3</term>
<term>Eif4a</term>
<term>Eif4e</term>
<term>Eif4f</term>
<term>Eif4g</term>
<term>Eifs</term>
<term>Embo</term>
<term>Emcv</term>
<term>Encephalomyocarditis virus</term>
<term>Entry site</term>
<term>Eukaryotic</term>
<term>Eukaryotic ribosomes</term>
<term>Eukaryotic translation initiation factor</term>
<term>Helicase</term>
<term>Hellen</term>
<term>Hepatitis</term>
<term>Host cell protein synthesis</term>
<term>Human rhinovirus</term>
<term>Initiation</term>
<term>Initiation codon</term>
<term>Initiation factors</term>
<term>Initiator trna</term>
<term>Internal initiation</term>
<term>Internal ribosome entry site</term>
<term>Internal ribosome entry sites</term>
<term>Ire</term>
<term>Ires activity</term>
<term>Ires elements</term>
<term>Ires factors</term>
<term>Ireses</term>
<term>Itafs</term>
<term>John wiley sons</term>
<term>Leaky scanning</term>
<term>Mrna</term>
<term>Nsp3</term>
<term>Nucleic acids</term>
<term>Pabp</term>
<term>Pestova</term>
<term>Picornavirus</term>
<term>Poliovirus</term>
<term>Protein</term>
<term>Protein synthesis</term>
<term>Reinitiation</term>
<term>Replication</term>
<term>Respiratory syndrome coronavirus</term>
<term>Ribosomal</term>
<term>Ribosomal subunit</term>
<term>Ribosomal subunits</term>
<term>Ribosome</term>
<term>Ribosome entry site</term>
<term>Ribosome shunting</term>
<term>Rna</term>
<term>Sarnow</term>
<term>Shunting</term>
<term>Sonenberg</term>
<term>Subunit</term>
<term>Translation</term>
<term>Translation initiation</term>
<term>Translational</term>
<term>Translational control</term>
<term>Untranslated</term>
<term>Untranslated region</term>
<term>Utrs</term>
<term>Viral</term>
<term>Viral ires</term>
<term>Viral mrna</term>
<term>Viral mrna translation</term>
<term>Viral mrnas</term>
<term>Viral proteins</term>
<term>Virol</term>
<term>Virus</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Viruses depend on cells for their replication but have evolved mechanisms to achieve this in an efficient and, in some instances, a cell‐type‐specific manner. The expression of viral proteins is frequently subject to translational control. The dominant target of such control is the initiation step of protein synthesis. Indeed, during the early stages of infection, viral mRNAs must compete with their host counterparts for the protein synthetic machinery, especially for the limited pool of eukaryotic translation initiation factors (eIFs) that mediate the recruitment of ribosomes to both viral and cellular mRNAs. To circumvent this competition viruses use diverse strategies so that ribosomes can be recruited selectively to viral mRNAs. In this review we focus on the initiation of protein synthesis and outline some of the strategies used by viruses to ensure efficient translation initiation of their mRNAs. Copyright © 2010 John Wiley & Sons, Ltd.</div>
</front>
</TEI>
<affiliations><list><country><li>Chili</li>
</country>
</list>
<tree><country name="Chili"><noRegion><name sortKey="L Pez Astra, Marcelo" sort="L Pez Astra, Marcelo" uniqKey="L Pez Astra M" first="Marcelo" last="L Pez-Lastra">Marcelo L Pez-Lastra</name>
</noRegion>
<name sortKey="L Pez Astra, Marcelo" sort="L Pez Astra, Marcelo" uniqKey="L Pez Astra M" first="Marcelo" last="L Pez-Lastra">Marcelo L Pez-Lastra</name>
<name sortKey="L Pez Astra, Marcelo" sort="L Pez Astra, Marcelo" uniqKey="L Pez Astra M" first="Marcelo" last="L Pez-Lastra">Marcelo L Pez-Lastra</name>
<name sortKey="Letelier, Alejandro" sort="Letelier, Alejandro" uniqKey="Letelier A" first="Alejandro" last="Letelier">Alejandro Letelier</name>
<name sortKey="Ramdohr, Pablo" sort="Ramdohr, Pablo" uniqKey="Ramdohr P" first="Pablo" last="Ramdohr">Pablo Ramdohr</name>
<name sortKey="Valiente Cheverria, Fernando" sort="Valiente Cheverria, Fernando" uniqKey="Valiente Cheverria F" first="Fernando" last="Valiente-Echeverría">Fernando Valiente-Echeverría</name>
<name sortKey="Vallejos, Maricarmen" sort="Vallejos, Maricarmen" uniqKey="Vallejos M" first="Maricarmen" last="Vallejos">Maricarmen Vallejos</name>
<name sortKey="Vera Tarola, Jorge" sort="Vera Tarola, Jorge" uniqKey="Vera Tarola J" first="Jorge" last="Vera-Otarola">Jorge Vera-Otarola</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002689 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002689 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:FA82ACC43D89E3B29F42BFE0780C0178E80FD4E4
   |texte=   Translation initiation of viral mRNAs
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration SRAS

Translation initiation of viral mRNAs

Translation initiation of viral mRNAs

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri